A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells

MicroRNAs (miRNAs) are regulators of several key patho-physiological processes, including cell cycle and apoptosis. Using microarray-based miRNA profiling in K562 cells, a model of chronic myeloid leukemia (CML), we found that the oncoprotein BCR-ABL1 regulates the expression of miR-21, an “onco-mic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Espadinha, Anne-Sophie, Prouzet-Mauléon, Valérie, Claverol, Stéphane, Lagarde, Valérie, Bonneu, Marc, Mahon, François-Xavier, Cardinaud, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652696/
https://ncbi.nlm.nih.gov/pubmed/29100302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19192
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