A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells

MicroRNAs (miRNAs) are regulators of several key patho-physiological processes, including cell cycle and apoptosis. Using microarray-based miRNA profiling in K562 cells, a model of chronic myeloid leukemia (CML), we found that the oncoprotein BCR-ABL1 regulates the expression of miR-21, an “onco-mic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Espadinha, Anne-Sophie, Prouzet-Mauléon, Valérie, Claverol, Stéphane, Lagarde, Valérie, Bonneu, Marc, Mahon, François-Xavier, Cardinaud, Bruno
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652696/
https://ncbi.nlm.nih.gov/pubmed/29100302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19192
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi