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Evidence of Missense Mutations on the Neuregulin 1 Gene Affecting Function of Prepulse Inhibition
BACKGROUND: Neuregulin 1 (NRG1) is one of the leading candidate genes in schizophrenia. Rodents with NRG1 knock-out showed significantly impaired prepulse inhibition (PPI) in the original report linking NRG1 to schizophrenia (Stefansson et al 2002). PPI is a widely used surrogate measure of psychosi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569848/ https://ncbi.nlm.nih.gov/pubmed/17631867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.05.011 |
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