Lack of association between COMT gene and deficit/nondeficit schizophrenia

BACKGROUND: The dopamine dysregulation hypothesis of schizophrenia posits that positive, negative and cognitive symptoms correlate with cortical/subcortical imbalances in dopaminergic transmission. A functional polymorphism (Val(158)Met) in the catechol-O-methyltransferase (COMT) gene is implicated...

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Detalhes bibliográficos
Main Authors: Wonodi, Ikwunga, Mitchell, Braxton D, Stine, O Colin, Hong, L Elliot, Elliott, Amie, Kirkpatrick, Brian, Carpenter, William T, Thaker, Gunvant K, Buchanan, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Short Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716164/
https://ncbi.nlm.nih.gov/pubmed/17173666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-2-42
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