Analysis of intergenic transcription in the human IL-4/IL-13 gene cluster

During the differentiation of naïve CD4(+) precursors to T helper 1 (Th1) or Th2 effector cells, several epigenetic changes occur in a lineage-specific manner at the IFN-γ or IL-4/IL-13 loci. These changes result in alterations in the chromatin structure of these loci and, hence, lineage-restricted...

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Detalhes bibliográficos
Main Authors: Rogan, David F., Cousins, David J., Santangelo, Samantha, Ioannou, Panayiotis A., Antoniou, Michael, Lee, Tak H., Staynov, Dontcho Z.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356970/
https://ncbi.nlm.nih.gov/pubmed/14983029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308327100
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