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Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis
IL-13 and IL-4 are central T helper 2 (Th2) cytokines in the immune system and potent activators of inflammatory responses and fibrosis during Th2 inflammation. Recent studies using Il13ra1(−/−) mice have demonstrated a critical role for IL-13 receptor (IL-13R) α1 in allergen-induced airway response...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386078/ https://ncbi.nlm.nih.gov/pubmed/18480254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802465105 |
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