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Conserved Intergenic Elements and DNA Methylation Cooperate to Regulate Transcription at the il17 Locus

Naive CD4(+) T cells can differentiate into distinct lineages with unique immune functions. The cytokines TGFβ and IL-6 promote the development of Th17 cells that produce IL-17, an inflammatory cytokine not expressed by other T helper lineages. To further understand how IL-17 production is controlle...

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Detalhes bibliográficos
Main Authors: Thomas, Rajan M., Sai, Hong, Wells, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408191/
https://ncbi.nlm.nih.gov/pubmed/22665476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351916
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