The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

In Huntington disease (HD), polyglutamine expansion in the huntingtin protein causes specific neuronal death. The consequences of the presence of mutant huntingtin in other tissues are less well understood. Here we propose that mutant huntingtin influences breast cancer progression. Indeed, we show...

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Hlavní autoři: Moreira Sousa, Cristovão, McGuire, John Russel, Thion, Morgane Sonia, Gentien, David, de la Grange, Pierre, Tezenas du Montcel, Sophie, Vincent-Salomon, Anne, Durr, Alexandra, Humbert, Sandrine
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2013
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569645/
https://ncbi.nlm.nih.gov/pubmed/23300147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201546
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