The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

In Huntington disease (HD), polyglutamine expansion in the huntingtin protein causes specific neuronal death. The consequences of the presence of mutant huntingtin in other tissues are less well understood. Here we propose that mutant huntingtin influences breast cancer progression. Indeed, we show...

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Autors principals: Moreira Sousa, Cristovão, McGuire, John Russel, Thion, Morgane Sonia, Gentien, David, de la Grange, Pierre, Tezenas du Montcel, Sophie, Vincent-Salomon, Anne, Durr, Alexandra, Humbert, Sandrine
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569645/
https://ncbi.nlm.nih.gov/pubmed/23300147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201546
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