The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

In Huntington disease (HD), polyglutamine expansion in the huntingtin protein causes specific neuronal death. The consequences of the presence of mutant huntingtin in other tissues are less well understood. Here we propose that mutant huntingtin influences breast cancer progression. Indeed, we show...

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Autori principali: Moreira Sousa, Cristovão, McGuire, John Russel, Thion, Morgane Sonia, Gentien, David, de la Grange, Pierre, Tezenas du Montcel, Sophie, Vincent-Salomon, Anne, Durr, Alexandra, Humbert, Sandrine
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2013
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569645/
https://ncbi.nlm.nih.gov/pubmed/23300147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201546
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