The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

In Huntington disease (HD), polyglutamine expansion in the huntingtin protein causes specific neuronal death. The consequences of the presence of mutant huntingtin in other tissues are less well understood. Here we propose that mutant huntingtin influences breast cancer progression. Indeed, we show...

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Detalhes bibliográficos
Main Authors: Moreira Sousa, Cristovão, McGuire, John Russel, Thion, Morgane Sonia, Gentien, David, de la Grange, Pierre, Tezenas du Montcel, Sophie, Vincent-Salomon, Anne, Durr, Alexandra, Humbert, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569645/
https://ncbi.nlm.nih.gov/pubmed/23300147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201546
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