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Evolutionary comparisons suggest many novel cAMP response protein binding sites in Escherichia coli

The cAMP response protein (CRP) is a transcription factor known to regulate many genes in Escherichia coli. Computational studies of transcription factor binding to DNA are usually based on a simple matrix model of sequence-dependent binding energy. For CRP, this model predicts many binding sites th...

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Detalhes bibliográficos
Main Authors: Brown, C. T., Callan, C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356963/
https://ncbi.nlm.nih.gov/pubmed/14983022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308628100
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