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The Discovery of Dabigatran Etexilate
Thromboembolic disease is a major cause of mortality and morbidity in the developed world and is caused by an excessive stimulation of coagulation. Thrombin is a key serine protease in the coagulation cascade and numerous efforts have been made to develop safe and effective orally active direct thro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569592/ https://ncbi.nlm.nih.gov/pubmed/23408233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00012 |
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