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Structure-guided residence time optimization of a dabigatran reversal agent
Novel oral anticoagulants are effective and safe alternatives to vitamin-K antagonists for anticoagulation therapy. However, anticoagulation therapy in general is associated with an elevated risk of bleeding. Idarucizumab is a reversal agent for the direct thrombin inhibitor, dabigatran etexilate (P...
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| Publicado en: | MAbs |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622598/ https://ncbi.nlm.nih.gov/pubmed/26047352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1057364 |
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