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Structure-guided residence time optimization of a dabigatran reversal agent

Novel oral anticoagulants are effective and safe alternatives to vitamin-K antagonists for anticoagulation therapy. However, anticoagulation therapy in general is associated with an elevated risk of bleeding. Idarucizumab is a reversal agent for the direct thrombin inhibitor, dabigatran etexilate (P...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:MAbs
मुख्य लेखकों: Schiele, Felix, van Ryn, Joanne, Litzenburger, Tobias, Ritter, Michael, Seeliger, Daniel, Nar, Herbert
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622598/
https://ncbi.nlm.nih.gov/pubmed/26047352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1057364
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