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The Discovery of Dabigatran Etexilate

Thromboembolic disease is a major cause of mortality and morbidity in the developed world and is caused by an excessive stimulation of coagulation. Thrombin is a key serine protease in the coagulation cascade and numerous efforts have been made to develop safe and effective orally active direct thro...

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Bibliografske podrobnosti
Main Authors: van Ryn, Joanne, Goss, Ashley, Hauel, Norbert, Wienen, Wolfgang, Priepke, Henning, Nar, Herbert, Clemens, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569592/
https://ncbi.nlm.nih.gov/pubmed/23408233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00012
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