Agonist-induced Ca(2+) entry determined by inositol 1,4,5-trisphosphate recognition

It has been considered that Ca(2+) release is the causal trigger for Ca(2+) entry after receptor activation. In DT40 B cells devoid of inositol 1,4,5-trisphosphate receptors (IP(3)R), the lack of Ca(2+) entry in response to receptor activation is attributed to the absence of Ca(2+) release. We revea...

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Main Authors: van Rossum, Damian B., Patterson, Randen L., Kiselyov, Kirill, Boehning, Darren, Barrow, Roxanne K., Gill, Donald L., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC356949/
https://ncbi.nlm.nih.gov/pubmed/14983008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308565100
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