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Stochastic dynamics of cancer initiation

Most human cancer types result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Once the first change (or changes) have arisen, tumorigenesis is initiated and the subsequent emergence of additional alterations drives progression to more aggressive and ultimately...

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Detalhes bibliográficos
Main Authors: Foo, Jasmine, Leder, Kevin, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569097/
https://ncbi.nlm.nih.gov/pubmed/21301064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/8/1/015002
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