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Prostaglandin E(2) EP(1) Receptor Inhibition Fails to Provide Neuroprotection in Surgically Induced Brain-Injured Mice

Recent trials have shown that the prostaglandin E(2) EP1 receptor is responsible for NMDA excitotoxicity in the brain after injury. Consequently, in this study, we investigated the use of SC-51089, a selective prostaglandin E(2) EP1 receptor antagonist, as a pre-treatment modality to decrease cell d...

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Main Authors: Khatibi, Nikan H., Jadhav, Vikram, Matus, Brenden, Fathali, Nancy, Martin, Robert, Applegate, Richard, Tang, Jiping, Zhang, John H.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569069/
https://ncbi.nlm.nih.gov/pubmed/21725768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-7091-0693-8_46
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