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Prostaglandin E(2) EP(1) Receptor Inhibition Fails to Provide Neuroprotection in Surgically Induced Brain-Injured Mice

Recent trials have shown that the prostaglandin E(2) EP1 receptor is responsible for NMDA excitotoxicity in the brain after injury. Consequently, in this study, we investigated the use of SC-51089, a selective prostaglandin E(2) EP1 receptor antagonist, as a pre-treatment modality to decrease cell d...

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Detalhes bibliográficos
Main Authors: Khatibi, Nikan H., Jadhav, Vikram, Matus, Brenden, Fathali, Nancy, Martin, Robert, Applegate, Richard, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569069/
https://ncbi.nlm.nih.gov/pubmed/21725768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-7091-0693-8_46
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