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Cyclooxygenase-2 Mediates Hyperbaric Oxygen Preconditioning Induced Neuroprotection in the Mouse Model of Surgical Brain Injury

BACKGROUND AND PURPOSE: We investigated the role of cyclooxygenase-2 (COX-2) in mechanisms of hyperbaric oxygen preconditioning (HBO-PC) in the mouse model of surgical brain injury (SBI). METHODS: C57BL mice were administered 100% oxygen for 1 hr at 2.5 ATA for 5 consecutive days and subjected to SB...

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Detalhes bibliográficos
Main Authors: Jadhav, Vikram, Ostrowski, Robert P., Tong, Wenni, Matus, Brenden, Jesunathadas, Rachel, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798800/
https://ncbi.nlm.nih.gov/pubmed/19628811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.549774
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