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Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase

Extracellular superoxide dismutase (SOD3) is a secreted enzyme that regulates levels of extracellular superoxide and protects the extracellular matrix from degradation by reactive species. The SOD3 protein contains a heparin-binding domain and resides in a microenvironment rich in other heparin-boun...

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Detalhes bibliográficos
Main Authors: Case, Adam J., Mezhir, James J., O'Leary, Brianne R., Hrabe, Jennifer E., Domann, Frederick E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569055/
https://ncbi.nlm.nih.gov/pubmed/23339859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1351000212Y.0000000028
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