The Folding of Human Active and Inactive Extracellular Superoxide Dismutases Is an Intracellular Event

Human extracellular superoxide dismutase (EC-SOD) is a tetrameric glycoprotein responsible for the removal of superoxide generated in the extracellular space. Two different folding variants of EC-SOD exist based on the disulfide bridge connectivity, resulting in enzymatically active (aEC-SOD) and in...

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Autori principali: Petersen, Steen V., Kristensen, Torsten, Petersen, Jane S., Ramsgaard, Lasse, Oury, Tim D., Crapo, James D., Nielsen, Niels C., Enghild, Jan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258874/
https://ncbi.nlm.nih.gov/pubmed/18385137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801548200
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