The spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells

BACKGROUND: Several differences exist between antigens on transfused red blood cells (RBCs) and other immunogens, including anatomical compartmentalization. Whereas antigens from microbial pathogens and solid organ transplants drain into local lymph nodes, circulating RBCs remain segregated in the p...

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Detalhes bibliográficos
Main Authors: Hendrickson, Jeanne E., Saakadze, Natia, Cadwell, Chantel M., Upton, Jason W., Mocarski, Edward S., Hillyer, Christopher D., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568957/
https://ncbi.nlm.nih.gov/pubmed/19413728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2009.02200.x
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