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MHC II on Transfused Murine Blood is Not Required for Alloimmunization Against MHC I

BACKGROUND AND OBJECTIVES: Transfusion of allogeneic platelet products can result in antibodies against donor MHC I antigens, leading to a refractory state to subsequent platelet transfusions. However, there is disagreement in the field regarding the molecular mechanisms of humoral alloimmunization....

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Detalhes bibliográficos
Main Authors: Gilson, Christopher R., Cadwell, Chantel M., Smith, Nicole H., Hendrickson, Jeanne E., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955847/
https://ncbi.nlm.nih.gov/pubmed/20546207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1423-0410.2010.01351.x
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