Treatment with Cationic Liposome-DNA Complexes (CLDC) Protects Mice from Lethal Western Equine Encephalitis Virus (WEEV) Challenge

Having recently characterized a CD-1 outbred mouse model of pathogenesis for Western equine encephalitis virus, we examined the possible protective effects of cationic lipid DNA complexes (CLDC) against encephalitic arboviral infection. In this investigation, mice were pre-treated, co-treated, or po...

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Autores principales: Logue, Christopher H., Phillips, Aaron T., Mossel, Eric C., Ledermann, Jeremy P., Welte, Thomas, Dow, Steve W., Olson, Ken E., Powers, Ann M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568752/
https://ncbi.nlm.nih.gov/pubmed/20452378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.04.013
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