Treatment with Cationic Liposome-DNA Complexes (CLDC) Protects Mice from Lethal Western Equine Encephalitis Virus (WEEV) Challenge

Having recently characterized a CD-1 outbred mouse model of pathogenesis for Western equine encephalitis virus, we examined the possible protective effects of cationic lipid DNA complexes (CLDC) against encephalitic arboviral infection. In this investigation, mice were pre-treated, co-treated, or po...

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Bibliographic Details
Main Authors: Logue, Christopher H., Phillips, Aaron T., Mossel, Eric C., Ledermann, Jeremy P., Welte, Thomas, Dow, Steve W., Olson, Ken E., Powers, Ann M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568752/
https://ncbi.nlm.nih.gov/pubmed/20452378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.04.013
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