Treatment with Cationic Liposome-DNA Complexes (CLDC) Protects Mice from Lethal Western Equine Encephalitis Virus (WEEV) Challenge

Having recently characterized a CD-1 outbred mouse model of pathogenesis for Western equine encephalitis virus, we examined the possible protective effects of cationic lipid DNA complexes (CLDC) against encephalitic arboviral infection. In this investigation, mice were pre-treated, co-treated, or po...

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Detalhes bibliográficos
Main Authors: Logue, Christopher H., Phillips, Aaron T., Mossel, Eric C., Ledermann, Jeremy P., Welte, Thomas, Dow, Steve W., Olson, Ken E., Powers, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568752/
https://ncbi.nlm.nih.gov/pubmed/20452378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.04.013
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