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Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons
L-type voltage gated calcium channels (LTCs) play an important role in neuronal development by promoting dendritic growth and arborization(1–3). A point mutation in Ca(V)1.2 causes Timothy Syndrome (TS)(4), a neurodevelopmental disorder associated with autism spectrum disorders (ASD). We report that...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568452/ https://ncbi.nlm.nih.gov/pubmed/23313911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3307 |
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