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Using iPS cells to investigate cardiac phenotypes in patients with Timothy Syndrome

Individuals with congenital or acquired prolongation of the QT interval, or long QT syndrome (LQTS), are at risk of life threatening ventricular arrhythmia 1, 2. LQTS is commonly genetic in origin but can also be caused or exacerbated by environmental factors1, 3. A missense mutation in the L-type c...

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Bibliografski detalji
Glavni autori: Yazawa, Masayuki, Hsueh, Brian, Jia, Xiaolin, Pasca, Anca M., Bernstein, Jonathan A., Hallmayer, Joachim, Dolmetsch, Ricardo E.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077925/
https://ncbi.nlm.nih.gov/pubmed/21307850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09855
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