Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome

BACKGROUND: Common genetic variation and rare mutations in genes encoding calcium channel subunits have pleiotropic effects on risk for multiple neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia. To gain further mechanistic insights by extending previous gene exp...

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Detaylı Bibliyografya
Asıl Yazarlar: Tian, Yuan, Voineagu, Irina, Paşca, Sergiu P, Won, Hyejung, Chandran, Vijayendran, Horvath, Steve, Dolmetsch, Ricardo E, Geschwind, Daniel H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213483/
https://ncbi.nlm.nih.gov/pubmed/25360157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0075-5
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