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MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling

Myeloid differentiation primary response protein 88 (MyD88) is classically known as an adaptor, linking TLR and IL-1R to downstream signaling pathways in the innate immune system. In addition to its role in innate immune cells, MyD88 has been shown to play an important role in T cells. How MyD88 reg...

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Detalhes bibliográficos
Main Authors: Chang, JiHoon, Burkett, Patrick R., Borges, Christopher M., Kuchroo, Vijay K., Turka, Laurence A., Chang, Cheong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568327/
https://ncbi.nlm.nih.gov/pubmed/23341605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206048110
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