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Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism

Bacteria develop resistance to many classes of antibiotics vertically, by engendering mutations in genes encoding transcriptional and translational apparatus. These severe adaptations affect global transcription, translation, and the correspondingly affected metabolism. Here, we characterize metabol...

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Bibliografische gegevens
Hoofdauteurs: Derewacz, Dagmara K., Goodwin, Cody R., McNees, C. Ruth, McLean, John A., Bachmann, Brian O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568320/
https://ncbi.nlm.nih.gov/pubmed/23341601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218524110
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