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Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism

Bacteria develop resistance to many classes of antibiotics vertically, by engendering mutations in genes encoding transcriptional and translational apparatus. These severe adaptations affect global transcription, translation, and the correspondingly affected metabolism. Here, we characterize metabol...

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Hlavní autoři: Derewacz, Dagmara K., Goodwin, Cody R., McNees, C. Ruth, McLean, John A., Bachmann, Brian O.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568320/
https://ncbi.nlm.nih.gov/pubmed/23341601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218524110
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