RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase

Activation-induced cytidine deaminase (AID) is essential for the somatic hypermutation (SHM) and class-switch recombination (CSR) of Ig genes. The mechanism by which AID triggers SHM and CSR has been explained by two distinct models. In the DNA deamination model, AID converts cytidine bases in DNA i...

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Detalhes bibliográficos
Main Authors: Liang, Guoxin, Kitamura, Kouichi, Wang, Zhe, Liu, Guangyan, Chowdhury, Sajeda, Fu, Weixin, Koura, Miki, Wakae, Kousho, Honjo, Tasuku, Muramatsu, Masamichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568302/
https://ncbi.nlm.nih.gov/pubmed/23341589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221921110
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