RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase

Activation-induced cytidine deaminase (AID) is essential for the somatic hypermutation (SHM) and class-switch recombination (CSR) of Ig genes. The mechanism by which AID triggers SHM and CSR has been explained by two distinct models. In the DNA deamination model, AID converts cytidine bases in DNA i...

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Bibliografiske detaljer
Main Authors: Liang, Guoxin, Kitamura, Kouichi, Wang, Zhe, Liu, Guangyan, Chowdhury, Sajeda, Fu, Weixin, Koura, Miki, Wakae, Kousho, Honjo, Tasuku, Muramatsu, Masamichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568302/
https://ncbi.nlm.nih.gov/pubmed/23341589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221921110
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