Type-I Interferon is Critical for FasL Expression on Lung Cells to Determine the Severity of Influenza

Infection of influenza A virus in mammals induces hyper lung pneumonia, which often causes lethal diseases. FasL is a specific ligand of Fas, which is a type-I transmembrane protein to induce cell death. Previously, it has been reported that the hyper induction of gene expression associated with Fas...

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Detalhes bibliográficos
Main Authors: Fujikura, Daisuke, Chiba, Satoko, Muramatsu, Daisuke, Kazumata, Mika, Nakayama, Yosuke, Kawai, Taro, Akira, Shizuo, Kida, Hiroshi, Miyazaki, Tadaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568138/
https://ncbi.nlm.nih.gov/pubmed/23408968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055321
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