Stimulation with the Aureobasidium pullulans-produced β-glucan effectively induces interferon stimulated genes in macrophage-like cell lines

A β-(1,3),(1,6)-D-glucan produced by A. pullulans (AP-PG) is known to be an immune stimulating agent. In this study, we demonstrate that the stimulation with AP-PG effectively induces the interferon (IFN) stimulated genes (ISGs) in macrophage-like cell lines. The ISGs, Mx1, ISG15, and viperin mRNAs...

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Autores principales: Muramatsu, Daisuke, Kawata, Koji, Aoki, Shiho, Uchiyama, Hirofumi, Okabe, Mitsuyasu, Miyazaki, Tadaaki, Kida, Hiroshi, Iwai, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998088/
https://ncbi.nlm.nih.gov/pubmed/24759061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04777
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