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Incremental parameter estimation of kinetic metabolic network models

BACKGROUND: An efficient and reliable parameter estimation method is essential for the creation of biological models using ordinary differential equation (ODE). Most of the existing estimation methods involve finding the global minimum of data fitting residuals over the entire parameter space simult...

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Bibliographic Details
Main Authors: Jia, Gengjie, Stephanopoulos, Gregory, Gunawan, Rudiyanto
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568022/
https://ncbi.nlm.nih.gov/pubmed/23171810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-142
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