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Sustained Ocular Hypertension Induces Dendritic Degeneration of Mouse Retinal Ganglion Cells That Depends on Cell Type and Location

PURPOSE. Glaucoma is characterized by retinal ganglion cell (RGC) death and frequently associated with elevated IOP. How RGCs degenerate before death is little understood, so we sought to investigate RGC degeneration in a mouse model of ocular hypertension. METHODS. A laser-induced mouse model of ch...

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Detalhes bibliográficos
Main Authors: Feng, Liang, Zhao, Yan, Yoshida, Miho, Chen, Hui, Yang, Jessica F., Kim, Ted S., Cang, Jianhua, Troy, John B., Liu, Xiaorong
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567754/
https://ncbi.nlm.nih.gov/pubmed/23322576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10791
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