70-kDa Heat Shock Cognate Protein hsc70 Mediates Calmodulin-dependent Nuclear Import of the Sex-determining Factor SRY

We recently showed that the developmentally important family of SOX (SRY (sex determining region on the Y chromosome)-related high mobility group (HMG) box) proteins require the calcium-binding protein calmodulin (CaM) for optimal nuclear accumulation, with clinical mutations in SRY that specificall...

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Bibliographic Details
Main Authors: Kaur, Gurpreet, Lieu, Kim G., Jans, David A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567665/
https://ncbi.nlm.nih.gov/pubmed/23235156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436741
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