Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal

The HMG (high-mobility group)-box-containing chromatin-remodelling factor SRY (sex-determining region on the Y chromosome) plays a key role in sex determination. Its role in the nucleus is critically dependent on two NLSs (nuclear localization signals) that flank its HMG domain: the C-terminally loc...

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Detalhes bibliográficos
Main Authors: Kaur, Gurpreet, Delluc-Clavieres, Aurelie, Poon, Ivan K. H., Forwood, Jade K., Glover, Dominic J., Jans, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911679/
https://ncbi.nlm.nih.gov/pubmed/20528776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091758
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