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A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin

An essential stage in endocytic coated vesicle recycling is the dissociation of clathrin from the vesicle coat by the molecular chaperone, 70-kDa heat-shock cognate protein (Hsc70), and the J-domain-containing protein, auxilin, in an ATP-dependent process. We present a detailed mechanistic analysis...

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Main Authors: Rothnie, Alice, Clarke, Anthony R., Kuzmic, Petr, Cameron, Angus, Smith, Corinne J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084117/
https://ncbi.nlm.nih.gov/pubmed/21482805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018845108
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