Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6)

The importance of E3 ubiquitin ligases, involved in the degradation of misfolded proteins or promotion of protein-protein interaction, is increasingly recognized in neurodegeneration. TDP-43 is a predominantly nuclear protein, which regulates the transcription of thousands of genes and binds to mRNA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hebron, Michaeline L., Lonskaya, Irina, Sharpe, Kaydee, Weerasinghe, Puwakdandawe P. K., Algarzae, Norah K., Shekoyan, Ashot R., Moussa, Charbel E.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567661/
https://ncbi.nlm.nih.gov/pubmed/23258539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419945
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados