Heparan Sulfate 6-O-Sulfotransferase Isoform-dependent Regulatory Effects of Heparin on the Activities of Various Proteases in Mast Cells and the Biosynthesis of 6-O-Sulfated Heparin

Heparan sulfate 6-O-sulfotransferase (HS6ST) is an enzyme involved in heparan sulfate (HS) biosynthesis that transfers a sulfate residue to position 6 of the GlcNAc/GlcNSO(3) residues of HS, and it consists of three isoforms. Heparin, the highly sulfated form of HS, resides in connective tissue mast...

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Bibliographic Details
Main Authors: Anower-E-Khuda, Md. Ferdous, Habuchi, Hiroko, Nagai, Naoko, Habuchi, Osami, Yokochi, Takashi, Kimata, Koji
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567626/
https://ncbi.nlm.nih.gov/pubmed/23223449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416651
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