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Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice

Genome-wide DNA demethylation, including the erasure of genome imprints, in primordial germ cells (PGCs) is a critical first step to creating a totipotent epigenome in the germ line. We show here that, contrary to the prevailing model emphasizing active DNA demethylation, imprint erasure in mouse PG...

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Bibliografski detalji
Glavni autori: Kagiwada, Saya, Kurimoto, Kazuki, Hirota, Takayuki, Yamaji, Masashi, Saitou, Mitinori
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567490/
https://ncbi.nlm.nih.gov/pubmed/23241950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.331
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