Novel Gα(S)-Protein Signaling Associated with Membrane-Tethered Amyloid Precursor Protein Intracellular Domain

Numerous physiological functions, including a role as a cell surface receptor, have been ascribed to Alzheimer's disease-associated amyloid precursor protein (APP). However, detailed analysis of intracellular signaling mediated by APP in neurons has been lacking. Here, we characterized intrinsi...

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Autors principals: Deyts, Carole, Vetrivel, Kulandaivelu S., Das, Shibandri, Shepherd, Yumiko M., Dupré, Denis J., Thinakaran, Gopal, Parent, Angèle T.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567462/
https://ncbi.nlm.nih.gov/pubmed/22302812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5433-11.2012
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