Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

A major unanswered question in neuroscience is whether there exists genomic variability between individual neurons of the brain, contributing to functional diversity or to an unexplained burden of neurological disease. To address this question, we developed a method to amplify genomes of single neur...

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Bibliografiske detaljer
Main Authors: Evrony, Gilad D., Cai, Xuyu, Lee, Eunjung, Hills, L. Benjamin, Elhosary, P. Christina, Lehmann, Hillel S., Parker, J.J., Atabay, Kutay D., Gilmore, Edward C., Poduri, Annapurna, Park, Peter J., Walsh, Christopher A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567441/
https://ncbi.nlm.nih.gov/pubmed/23101622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.035
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