Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

A major unanswered question in neuroscience is whether there exists genomic variability between individual neurons of the brain, contributing to functional diversity or to an unexplained burden of neurological disease. To address this question, we developed a method to amplify genomes of single neur...

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Autors principals: Evrony, Gilad D., Cai, Xuyu, Lee, Eunjung, Hills, L. Benjamin, Elhosary, P. Christina, Lehmann, Hillel S., Parker, J.J., Atabay, Kutay D., Gilmore, Edward C., Poduri, Annapurna, Park, Peter J., Walsh, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567441/
https://ncbi.nlm.nih.gov/pubmed/23101622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.035
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