Macrophage/epithelial cell CCL2 contributes to rhinovirus-induced hyperresponsiveness and inflammation in a mouse model of allergic airways disease

Human rhinovirus (HRV) infections lead to exacerbations of lower airways disease in asthmatic patients but not in healthy individuals. However, underlying mechanisms remain to be completely elucidated. We hypothesized that the Th2-driven allergic environment enhances HRV-induced CC chemokine product...

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Hauptverfasser: Schneider, Dina, Hong, Jun Young, Bowman, Emily R., Chung, Yutein, Nagarkar, Deepti R., McHenry, Christina L., Goldsmith, Adam M., Bentley, J. Kelley, Lewis, Toby C., Hershenson, Marc B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567365/
https://ncbi.nlm.nih.gov/pubmed/23204071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00182.2012
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