TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4

Recent findings indicate that TLR3 polymorphisms increase susceptibility to enteroviral myocarditis and inflammatory dilated cardiomyopathy (iDCM) in patients. TLR3 signaling has been found to inhibit coxsackievirus B3 (CVB3) replication and acute myocarditis in mouse models, but its role in the pro...

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Autores principales: Abston, Eric D., Coronado, Michael J., Bucek, Adriana, Onyimba, Jennifer A., Brandt, Jessica E., Frisancho, J. Augusto, Kim, Eunyong, Bedja, Djahida, Sung, Yoon-kyu, Radtke, Andrea J., Gabrielson, Kathleen L., Mitzner, Wayne, Fairweather, DeLisa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Call for Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567355/
https://ncbi.nlm.nih.gov/pubmed/23255589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00516.2011
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