Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model

Despite advances in the therapeutic use of recombinant granulocyte colony-stimulating factor (G-CSF) to promote granulopoiesis of human hematopoietic stem cells (HSCs), neutropenia remains one of the most serious complications of cancer chemotherapy. We discovered that retinoid agonist Am80 (tamibar...

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Detalhes bibliográficos
Main Authors: Ding, Wanjing, Shimada, Hiroyuki, Li, Lin, Mittal, Rahul, Zhang, Xiaokun, Shudo, Koichi, He, Qiaojun, Prasadarao, Nemani V., Wu, Lingtao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567346/
https://ncbi.nlm.nih.gov/pubmed/23243275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-436022
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